Carcinoma basoescamoso na pálpebra inferior: reconstrução com enxerto de cartilagem auricular associado ao retalho de Tripier após cirurgia de Mohs / Basosquamous carcinoma in lower eyelid: reconstruction with auricular cartilage graft associated with the Tripier flap after Mohs surgery

O carcinoma basoescamoso tem alto potencial de recorrência local e metástase, especialmente quando recidivado e na localização periocular. Um paciente masculino de 49 anos foi submetido a cirurgia micrográfica de Mohs e reconstrução subtotal da pálpebra inferior com enxerto de cartilagem da hélice da orelha associado ao retalho de Tripier, evoluindo com ótimo resultado funcional e estético

Basosquamous carcinoma has a high potential for local recurrence and metastasis, especially when it recurs and at the periocular area. A 49-year-old man underwent Mohs micrographic surgery and subtotal reconstruction of the lower eyelid with cartilage graft from the helix of the ear associated with the Tripier flap, evolving with excellent functional and aesthetic results

Periungual basal cell carcinoma

Abstract: Periungual basal cell carcinoma is rare and needs to be differentiated from other common diseases that affect this region. Several factors are associated with the development of this tumor, and sun damage seems to play an important role in its pathogenesis. Dermoscopy of clinically indolent lesions on the nail unit can shorten the diagnostic process and avoid destructive treatment and functional damage.

Basosquamous Carcinoma of the Hand in a Radiologist with Prolonged Radiation Exposure

Basosquamous carcinoma is a rare epithelial neoplasm, mostly occurring on the head and neck area. There are few reports of basosquamous carcinoma on the finger. Here, the authors experienced treatment of basosquamous carcinoma on the finger in a radiologist. Treatment was successful by the wide excision and the cross-finger flap operation with a split-thickness skin graft and K-wire fixation. The rare finger basosquamous carcinoma case in our study is likely to be linked with radiation. Considering of the high reliance of C-arm during hand surgeries, we think that the hand of the surgeons should be more strictly protected.

Carcinoma basoescamoso na cidade de Loja, Equador / Basosquamous carcinoma in the city of Loja, Equador

Introdução: O Equador encontra-se na latitude 0 grau, 0’0’’, posição terrestre exposta a maior quantidade de radiação solar do planeta, especialmente aos raios UVA e UVB que predispõe a dano solar e aparecimento de câncer de pele. Objetivos: Nesse contexto, decidimos descrever a presença de carcinoma basoescamoso em uma cidade ao sul do Equador. Casuística e Métodos: Realizamos uma revisão de prontuários dos pacientes com diagnóstico de carcinoma basocelular da região cérvico-facial submetidos a cirurgia como tratamento, entre 2009 e 2013 no único hospital oncológico da cidade. Resultados: Encontramos 186 carcinomas basocelulares e 17 desses tumores eram basoescamosos. A maior porcentagem desse tipo de tumor afetaram principalmente mulheres; a idade média foi 54,9 anos. A raça branca foi mais afetada (58,8%), com elevada taxa relativa de não-brancos (41,2%). Nariz, lábio e couro cabeludo foram as áreas mais acometidas. Dez casos apareceram em zona de alto risco (58,8%). A invasão perineural e angiolinfática esteve presente em mais da metade dos casos. Nossos resultados mostram uma frequência superior de carcinomas basoescamosos entre os carcinomas basocelulares em relação a maior parte das publicações internacionais. As razões para tal achado são multifatoriais e podem incluir viés de seleção, distribuição étnica diferenciada da população equatoriana e maior incidência de radiação solar nesta região.

Introduction: Equador is at 0, 0’0’ degrees latitude, therefore is exposed to a largest amount of solar radiation the planet, especially to UVA and UVB rays what predisposes to cell damage and the onset of skin cancer. Objectives: In this context, we decide to describe the presence of the basosquamous carcinoma in one city at the south of Equador. Casuistics and Methods: We realize a review from medical charts of every patient with the diagnosis of cervicofacial basal cell carcinoma and that went to surgery for treatment, during the period from 2009 and 2013 at the only oncological hospital in the city. Results: We found 186 basal cell carcinomas and 17 of these tumors were basosquamous carcinomas. The highest percentage of this kind of tumor affected mostly women, the mean age was 54,9 years. The white people was the most affected (58,8%), with a relative high rate of nonwhites (41,2%). The nose, lips and scalp were the areas that arise this tumor. Ten of the cases appear in the high risk zone (58,8%). Characteristics such as perineural and angiolymphatic were present in more than half of the patients.

Application of Sentinel Lymph Node Biopsy in Cutaneous Basosquamous Carcinoma

Basosquamous carcinoma of the skin is a relatively rare cutaneous neoplasm that has significant metastatic potential and a metastatic rate greater than that of basal cell and squamous cell carcinoma. We describe the use of lymphatic mapping and sentinel lymph node biopsy in a 63-year-old man after identification of basosquamous carcinoma. Sentinel lymph node biopsy, which is a standard tool to detect regional lymphatic metastasis in cutaneous melanoma, has been rarely employed to detect lymphatic metastasis of basosquamous carcinoma. The approach was successful in detecting a regional lymphatic metastasis of two nodal basins with minor morbidity. Sentinel lymph node biopsy may be useful for certain high-risk lesions of basosquamous carcinoma.

A Case of Basosquamous Carcinoma of the Eyelid

PURPOSE: To report a rare case of basosquamous carcinoma of the eyelid, an aggressive tumor with a higher tendency for recurrence and metastasis. CASE SUMMARY: An 87-year-old woman presented with a painful mass and bloody exudates at the left lateral lower eyelid. Four years previous, the patient was diagnosed with basosquamous carcinoma of the left lower eyelid after biopsy at another hospital. At that time, she was unable to receive operation because she had suffered from a serious heart condition. With time, the left lower eyelid mass continued to grow and symptoms and signs of pain and bloody exudates appeared. The patient underwent surgery for complete tumor resection and repair and the biopsy of a specimen showed tumor-free margins and no metastasis to distal sites. CONCLUSIONS: Basosquamous carcinoma is a subtype of basal cell carcinoma with aggressive behavior and a higher tendency for recurrence and metastasis. However, our case showed no recurrence with no metastasis to the nearby lymph nodes, vessels, or nerves. We report a case of basosquamous carcinoma of the eyelid at old age that was cured after operative resection.

Carcinoma basoescamoso: reporte de un caso con exposición crónica a arsénico ambiental / Basosquamous carcinoma: a case report with chronic environmental arsenic exposition

Basosquamous carcinoma is a relatively rare cutaneous tumour that shares some characteristics of both basal cell and squamous cell carcinoma. Currently most dermatologists consider that it represents a subtype of basal cell carcinoma with a more aggressive behaviour. The clinical presentation is non-specific and in general the diagnosis is made after the histopathological studies. The prevalence is higher in male patients, during the seventh decade and it tends to appear on sun exposed areas. Many authors compare its behaviour with squamous cell carcinoma. We present the case of a 44 years old male patient with a history of chronic arsenic exposure that presented a firm tumor in the left inguinal region and the biopsy showed basosquamous carcinoma with lymphatic involvement. This case shows an atypical presentation because of its localization and the appearance 20 years before the mean age reported in the literature. This could be explained by chronic environmental arsenic exposure, a well known risk factor for the development of cutaneous tumours.

El carcinoma basoescamoso es una neoplasia cutánea relativamente rara que reúne características de carcinoma basocelular y espinocelular. Actualmente la mayoría de los dermatólogos reconocen que este es un subtipo del carcinoma basocelular con comportamiento muchísimo más agresivo. Su presentación clínica es inespecífica y en general su diagnóstico se realiza sólo después de la biopsia. Predomina en pacientes de sexo masculino durante la séptima década de la vida y tiende a aparecer en regiones fotoexpuestas. Muchos autores igualan su comportamiento al del carcinoma espinocelular. Se presenta el caso de un paciente, de sexo masculino, de 44 años de edad, con antecedente de exposición a arsénico medioambiental crónica, que presentó aumento de volumen, duro en la región inguinal izquierda, cuya biopsia fue compatible con carcinoma basoescamoso con compromiso linfático. El caso de nuestro paciente muestra una presentación atípica por su localización y por la aparición 20 años antes de la media de edad reportada en la literatura. Esto podría ser explicado por la exposición crónica a arsénico, conocido factor de riesgo para carcinogénesis cutánea.

Periocular metatypical cell carcinoma with scleral infiltration.

A 60-year-old male, laborer by occupation, presented with an ulcerative lesion of medial canthus in the left eye along with infiltration and adhesion of lids to globe. He had decreased vision and restricted extraocular movements. Exenteration with skin grafting was done. Histopathologically it was diagnosed as periocular metatypical cell carcinoma with scleral infiltration. Any suspicious lesion should be diagnosed and treated early so as to prevent such extensive damage.

Comparative Analysis of Squamous Cell Differentiation by Histologic Subtypes in Basal Cell Carcinoma / 대한피부과학회지

BACKGROUND: There has been no general agreement on classifying basal cell carcinoma (BCC), and little is known about the squamous cell differentiations of each subtype of BCC. BCC is a locally-invasive tumor, but its aggressive forms tend to recur and metastasize. OBJECTIVE: We have compared the histolopathological subtypes of BCC by squamous differentiation, with special emphasis on basosquamous carcinoma and the difference between the non- aggressive and aggressive forms of BCC. MATERIALS AND METHOD: A total of 87 BCC specimens were collected from the 7 branch hospitals of The Catholic University of Korea from July 1997 to June 2003. RESULTS: 1. The 87 samples were divided into 6 subtypes: 18 nodular, 19 nodular infiltrative, 12 micronodular, 14 infiltrative, 11 morpheaform, 13 basosquamous. Overall, 18 samples were classified as non- aggressive and the remaining 69 as aggressive. 2.In nodular-infiltrative BCC and basosquamous carcinoma, squamous cell differentiation was significantly more prominent than in the nodular BCC. CONCLUSION: Squamous cell differentiation should be considered as one of the aggressive markers, especially in nodule-forming BCC.

Basosquamous Carcinoma / 대한피부과학회지

An 89-Year-old female patient had had a pea-sized encrusted ulcer on the vermillion border of her right upper lip for 4 years. Histopathological features of the biopsy specimen consisted of tumor islands with peripheral, palisading basaloid cells, some of which had become transformed into atypical, dyskeratotic squamous cells with ample eosinophilic cytoplasm in their centers. Total excision was advised.